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Hoteliers! Is your information accurate? UPDATE HERE OverviewPhotos & VideoLocal Info Homewood Suites by Hilton Carlisle Location & Neighborhood Location Description: near historical downtown Carlisle, with quick access to I-76 & I-81.Hotel Location: Highway Nearby Airports Harrisburg Intl (22 miles east)Lancaster (47.50 miles east)University Park (56 miles northwest)