2018 U.S.-Booked Air Volume: $48 million
Science and technology firm Danaher's business units range from environmental and applied solutions and life sciences to diagnostics and dental. The company earned $2.7 billion in 2018, up 7 percent from 2017. Meanwhile, according to a BTN estimate, U.S.-booked air volume slid in 2018 from 2017's $52 million. The decrease occurred despite growth from 67,000 employees in 2017 to more than 71,000. The company also closed acquisitions totaling $2.2 billion in 2018, including biotech firm Integrated DNA Technologies and software management company Blue Software. It also spun off its dental operations into a publicly traded company called dentalco.